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ConditionResearch Study Main I/EStudy LinkPIPrimary CoordinatorPC NumberBack-Up CoordinatorBC Number
GN - all typesGDCN RegistryKidney disease, healthy controls, disease controlsRegistry, BiobankNAFalklmccabe@email.unc.edu919-445-2635
AKIKPMP AKI CohorteGFR >45; creatinine >=1.5 times baseline, evidence of AKIObservational; BiobankNCT04334707Mottlanne_froment@med.unc.edu919-445-2622
ANCAPathobiology of ANCANew or flaring ANCATranslationalNAFalkmmcollie@live.unc.edu919-445-2696
ANCACD5 WATCH (B cell recovery)1 month in remission (after 1st treatment or 1st relapse in AAV)DeviceNCT03906227Derebailanne_froment@med.unc.edu919-445-2622
Anti-GBMGOOD-IDES-O2 (lmlifidase)Newly diagnosed (<14 days), Hematuria, eGFR<20Phase 3NCT05679401Derebailanne_froment@med.unc.edu919-445-2622
IgANASSIST (Atrasentan)Biopsy proven IgA; eGFR >=30; Receiving RAS; On or willing to be on SGLT2 inhibitorPhase
MNREBOOT (belimumab and rituximab)primary MN biopsied in last 3 years; age 18-75; eGFR > 40; proteinuria > 4g/day; BP < 140/90Phase 2NCT03949855Derebailanne_froment@med.unc.edu919-445-2622
MN, MCD, FSGSNEPTUNE ( Nephrotic Syndrome Study Network)Must be enrolled PRE BIOPSY; UPCR≥1.5Observational; BiobankNCT01209000Derebail/Gibson (Peds)sara_kelley@med.unc.edu919-445-2658
MN, MCD, FSGS, IgACureGN (Cure Glomerulonephropathy Network)Biopsied in the last 5 years; ancillary study now available for diabetes at biopsyObservational; BiobankNAMottltcamero@email.unc.edu919-445-2898caroline_poulton@unc.edu919-445-2636
PEDS: FSGS, MCD, IGAN, IGAVEPPIK (Sparsenten)eGFR ≥30; BP between 5th-95th percentile; UP/C ≥1.0g/g; biopsy proven diseasePhase 2NCT05003986Gibsonanne_froment@med.unc.edu919-445-2622
LUPUSMiSLE - Mesenchymal Stem Cells for refractory lupus BILAG A or B, Sledai score > 5, completed 6 months induction therapyPhase 2NCT02633163Sheikhjulie_walker@med.unc.edu919-843-6619
LUPUSVOCAL (Voclosporin)Ages 12-17, SLE biopsied in last year, evidence of active nephritisPhase 3NCT05288855
Nephrotic SyndromeINShore (Obinituzimab)Ages 2-25; frequently relapsing/steroid dependednt NS diagnosed prior to age 18, UPCR<=0.2g/g, at least 1 relpase in past 6 monthsPhase 3NCT05627557Gibsonanne_froment@med.unc.edu919-445-2622
DKDTRIDENTDiabetes, >= 18yo, getting a biopsy: must be enrolled PRE-BIOPSYObservational; BiobankNCT02986984Mottlsara_kelley@med.unc.edu919-445-2658anne_froment@med.unc.edu919-445-2622
DKDCONFIDENCEType 2 diabetes, eGFR 30-75, UACR 300-5000 mg/gPhase 2NCT05254002Mottlsara_kelley@med.unc.edu919-445-2658anne_froment@med.unc.edu919-445-2622
Undergoing CEUSContrast Enhanced Ultrasound of the Kidneys RegistryPatients undergoing CEUSRegistryNAChanganne_froment@med.unc.edu919-445-2622
CKDKPMP CKD CohorteGFR 30-59; eGFR >=60 if albuminuria/proteinuria presentObservational; BiobankNCT04334707Mottlanne_froment@med.unc.edu919-445-2622
CKDTHRiVE (Vascular Access Education)eGFR <= 20 or Kidney Failure Risk Equation Score >40%; documentation of discussion about dialysisInterventionalNCT05997875Flytheveronica_joseph@med.unc.edu919-966-4615
CKD, Non-DiabeticAMPLITUDE18-60 years old, UPCR >0.7g/g - <10g/g, eGFR >25 - <75Phase 2/3NCT05312879Derebailsara_kelley@med.unc.edu919-445-2658anne_froment@med.unc.edu919-445-2622
DialysisTwoPLUS (Incremental vs Conventional Dialysis)Incident kidney dysfunction requiring dialysis within the next 6 weeks; Kidney urea clearance ≥3.5; urine volume ≥500 mL/24
TransplantEFFEKTOR (Finerenone)Adults 1-10 years post txp; eGFR >=25; UACR >=30Phase

Contact by phone: Anne Froment 5-2622, Sara Kelley 5-2658, Caroline Poulton 5-2636