2018 Publications

  1. Mottl AK, Gasim A, Schober FP, Hu Y, Dunnon AK, Hogan SL, Jennette JC. Segmental Sclerosis and Extracapillary Hypercellularity Predict Diabetic ESRD. J Am Soc Nephrol. 2018 Feb;29(2):694-703. (Read article)
  2. Assimon MM, Wang L, Flythe JE. Failed Target Weight Achievement Associates with Short-Term Hospital Encounters among Individuals Receiving Maintenance Hemodialysis. Assimon MM, Wang L, Flythe JE. J Am Soc Nephrol. 2018 May 23 (Read abstract)
  3. Assimon MM, Brookhart MA, Fine JP, Heiss G, Layton JB, Flythe JE. A Comparative Study of Carvedilol Versus Metoprolol Initiation and 1-Year Mortality Among Individuals Receiving Maintenance Hemodialysis. Am J Kidney Dis. 2018 Apr 10. (Read abstract)
  4. Flythe JE, Hilliard T, Castillo G, Ikeler K, Orazi J, Abdel-Rahman E, Pai AB, Rivara MB, St Peter WL, Weisbord SD, Wilkie C, Mehrotra R. Symptom Prioritization among Adults Receiving In-Center Hemodialysis: A Mixed Methods Study. Clin J Am Soc Nephrol. 2018 May 7;13(5):735-745 (Read abstract)
  5. Assimon MM, Wang L, Flythe JE. Intradialytic Hypertension Frequency and Short-Term Clinical Outcomes Among Individuals Receiving Maintenance Hemodialysis. Am J Hypertens. 2018 Feb 9;31(3):329-339. (Read abstract)
  6. Mu Y, Chin AI, Kshirsagar AV, Zhang Y, Bang H. Regional and Temporal Variations in Comorbidity Among US Dialysis Patients: A Longitudinal Study of Medicare Claims Data.Inquiry. 2018 Jan-Dec;55 (read abstract: (Read abstract)
  7. Hardy ST, Zeng D, Kshirsagar AV, Viera AJ, Avery CL, Heiss G. Primary prevention of chronic kidney disease through population-based strategies for blood pressure control: The ARIC study.J Clin Hypertens (Greenwich). 2018 Jun;20(6):1018-1026. (Read abstract)
  8. van Daalen EE, Jennette JC, McAdoo SP, Pusey CD, Alba MA, Poulton CJ, Wolterbeek R, Nguyen TQ, Goldschmeding R, Alchi B, Griffiths M, de Zoysa JR, Vincent B, Bruijn JA, Bajema IM. Predicting Outcome in Patients with Anti-GBM Glomerulonephritis. Clin J Am Soc Nephrol. 2018 Jan 6;13(1):63-72. (Read abstract)

2017 Publications

  1. O’Shaughnessy MM, Hogan SL, Poulton CJ, Falk RJ, Singh HK, Nickeleit V, Jennette JC. Temporal and Demographic Trends in Glomerular Disease Epidemiology in the Southeastern United States, 1986-2015. Clin J Am Soc Nephrol. 2017 Apr 3;12(4):614-623. (Read abstract)
  2. Flythe JE, Hilbert J, Kshirsagar AV, Gilet CA. Psychosocial Factors and 30-Day Hospital Readmission among Individuals Receiving Maintenance Dialysis: A Prospective Study. Am J Nephrol. 2017;45(5):400-408. (Read abstract)
  3. Brown LC, Jobson MA, Payan Schober F, Chang EH, Falk RJ, Nachman PH, Pendergraft WF. The Evolving Role of Rituximab in Adult Minimal Change Glomerulopathy. Am J Nephrol. 2017;45(4):365-372. (Read abstract)
  4. Payan Schober F, Jobson MA, Poulton CJ, Singh HK, Nickeleit V, Falk RJ, Jennette JC, Nachman PH, Pendergraft Iii WF. Clinical Features and Outcomes of a Racially Diverse Population with Fibrillary Glomerulonephritis. Am J Nephrol. 2017;45(3):248-256. (Read abstract)
  5. Jones BE, Yang J, Muthigi A, Hogan SL, Hu Y, Starmer J, Henderson CD, Poulton CJ, Brant EJ, Pendergraft WF 3rd, Jennette JC, Falk RJ, Ciavatta DJ. Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis. J Am Soc Nephrol. 2017 Apr;28(4):1175-1187 (Read abstract)
  6. Flythe JE, Narendra JH, Dorough A, Oberlander J, Ordish A, Wilkie C, Dember LM. Perspectives on Research Participation and Facilitation Among Dialysis Patients, Clinic Personnel, and Medical Providers: A Focus Group Study. Am J Kidney Dis. 2017 Dec 19. pii: S0272-6386(17)31041-7. (Read abstract)
  7. Schober GS, Wenger JB, Lee CC, Oberlander J, Flythe JE. Dialysis Patient Perspectives on CKD Advocacy: A Semistructured Interview Study. Am J Kidney Dis. 2017 Jan;69(1):29-40 (read abstract: (Read abstract)
  8. O’Shaughnessy MM, Jobson MA, Sims K, Liberty AL, Nachman PH, Pendergraft WF. Pregnancy Outcomes in Patients with Glomerular Disease Attending a Single Academic Center in North Carolina. Am J Nephrol. 2017;45(5):442-451. (Read abstract)

2016 Publications

  1. Yang J, Ge H, Poulton CJ, Hogan SL, Hu Y, Jones BE, Henderson CD, McInnis EA, Pendergraft WF 3rd, Jennette JC, Falk RJ, Ciavatta DJ. Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Clin Epigenetics. 2016 Aug 12;8:85. eCollection 2016. (Read abstract)
  2. Assimon MM, Wenger JB, Wang L, Flythe JE. Ultrafiltration Rate and Mortality in Maintenance Hemodialysis Patients. Am J Kidney Dis. 2016 Dec;68(6):911-922 (Read abstract)
  3. Laurin LP, Gasim AM, Derebail VK, McGregor JG, Kidd JM, Hogan SL, Poulton CJ, Detwiler RK, Jennette JC, Falk RJ, Nachman PH. Renal Survival in Patients with Collapsing Compared with Not Otherwise Specified FSGS. Clin J Am Soc Nephrol. 2016 Oct 7;11(10):1752-1759. (Read abstract)
  4. Lee T, Derebail VK, Kshirsagar AV, Chung Y, Fine JP, Mahoney S, Poulton CJ, Lionaki S, Hogan SL, Falk RJ, Cattran DC, Hladunewich M, Reich HN, Nachman PH. Patients with primary membranous nephropathy are at high risk of cardiovascular events. Kidney Int. 2016 May;89(5):1111-8. (Read abstract)
  5. Laurin LP, Gasim AM, Poulton CJ, Hogan SL, Jennette JC, Falk RJ, Foster BJ, Nachman PH. Treatment with Glucocorticoids or Calcineurin Inhibitors in Primary FSGS. Clin J Am Soc Nephrol. 2016 Mar 7;11(3):386-94. (Read article)
  6. Rhee RL, Hogan SL, Poulton CJ, McGregor JA, Landis JR, Falk RJ, Merkel PA. Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Renal Disease. Arthritis Rheumatol. 2016 Jul;68(7):1711-20. (Read abstract)

2015 Publications

  1. Reynolds J, Preston GA, Pressler BM, Hewins P, Brown M, Roth A, Alderman E, Bunch D, Jennette JC, Cook HT, Falk RJ, Pusey CD. Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by ‘autoantigen complementarity’. J Autoimmun. 2015;59:8-18. Epub 2015/04/07. doi: 10.1016/j.jaut.2015.01.003. PubMed PMID: 25841937; PMCID: PMC4459745. (Read Abstract)
  2. Pendergraft WF, 3rd, Falk RJ. Understanding the role of rituximab in ANCA GN: regressing toward the mean. J Am Soc Nephrol. 2015;26(4):771-4. Epub 2014/11/09. doi: 10.1681/asn.2014100997. PubMed PMID: 25381425; PMCID: PMC4378114. (Read Text)
  3. McInnis EA, Badhwar AK, Muthigi A, Lardinois OM, Allred SC, Yang J, Free ME, Jennette JC, Preston GA, Falk RJ, Ciavatta DJ. Dysregulation of autoantigen genes in ANCA-associated vasculitis involves alternative transcripts and new protein synthesis. J Am Soc Nephrol. 2015;26(2):390-9. Epub 2014/07/26. doi: 10.1681/asn.2013101092. PubMed PMID: 25060059; PMCID: PMC4310652. (Read Abstract)
  4. McGregor JG, Negrete-Lopez R, Poulton CJ, Kidd JM, Katsanos SL, Goetz L, Hu Y, Nachman PH, Falk RJ, Hogan SL. Adverse events and infectious burden, microbes and temporal outline from immunosuppressive therapy in antineutrophil cytoplasmic antibody-associated vasculitis with native renal function. Nephrol Dial Transplant. 2015;30 Suppl 1:i171-81. Epub 2015/03/26. doi: 10.1093/ndt/gfv045. PubMed PMID: 25805747. (Read Abstract)
  5. McGregor JG, Hogan SL, Kotzen ES, Poulton CJ, Hu Y, Negrete-Lopez R, Kidd JM, Katsanos SL, Bunch DO, Nachman PH, Falk RJ. Rituximab as an immunosuppressant in antineutrophil cytoplasmic antibody-associated vasculitis. Nephrol Dial Transplant. 2015;30 Suppl 1:i123-31. Epub 2015/03/26. doi: 10.1093/ndt/gfv076. PubMed PMID: 25805743; PMCID: PMC4447867. (Read Abstract)
  6. Jennette JC, Falk RJ. ANCAs are also antimonocyte cytoplasmic autoantibodies. Clin J Am Soc Nephrol. 2015;10(1):4-6. Epub 2014/12/18. doi: 10.2215/cjn.11501114. PubMed PMID: 25516916; PMCID: PMC4284421. (Read Text)
  7. Jain K, Gupta A, Singh HK, Nickeleit V, Kshirsagar AV. Bile cast nephropathy. Kidney Int. 2015;87(2):484. Epub 2015/01/31. doi: 10.1038/ki.2014.233. PubMed PMID: 25635725. (Read Text)
  8. Grubbs V, Vittinghoff E, Beck JD, Kshirsagar AV, Wang W, Griswold ME, Powe NR, Correa A, Young B. The Association Between Periodontal Disease and Kidney Function Decline in African Americans: The Jackson Heart Study. J Periodontol. 2015:1-11. Epub 2015/06/26. doi: 10.1902/jop.2015.150195. PubMed PMID: 26110451. (Read Abstract)
  9. Gibson KL, Glenn D, Ferris ME. Back to the future: therapies for idiopathic nephrotic syndrome. Blood Purif. 2015;39(1-3):105-9. Epub 2015/02/11. doi: 10.1159/000368951. PubMed PMID: 25659288. (Read Abstract)
  10. Folsom AR, Tang W, Roetker NS, Kshirsagar AV, Derebail VK, Lutsey PL, Naik R, Pankow JS, Grove ML, Basu S, Key NS, Cushman M. Prospective study of sickle cell trait and venous thromboembolism incidence. J Thromb Haemost. 2015;13(1):2-9. Epub 2014/11/14. doi: 10.1111/jth.12787. PubMed PMID: 25393788; PMCID: PMC4294976. (Read Abstract)
  11. Flythe JE, Kshirsagar AV, Falk RJ, Brunelli SM. Associations of Posthemodialysis Weights above and below Target Weight with All-Cause and Cardiovascular Mortality. Clin J Am Soc Nephrol. 2015;10(5):808-16. Epub 2015/04/12. doi: 10.2215/cjn.10201014. PubMed PMID: 25862779; PMCID: PMC4422248. (Read Abstract)
  12. Ferris ME, Ferris MT, Okumura MJ, Cohen SE, Hooper SR. Health care transition preparation in youth with chronic conditions: working towards translational evidence with a patient perspective. J Pediatr Rehabil Med. 2015;8(1):31-7. Epub 2015/03/05. doi: 10.3233/prm-150316. PubMed PMID: 25737346. (Read Abstract)
  13. Ferris ME, Cuttance JR, Javalkar K, Cohen SE, Phillips A, Bickford K, Gibson K, Ferris MT, True K. Self-management and transition among adolescents/young adults with chronic or end-stage kidney disease. Blood Purif. 2015;39(1-3):99-104. Epub 2015/02/11. doi: 10.1159/000368978. PubMed PMID: 25662749. (Read Abstract)
  14. Chang EH, Gasim AH, Kerber ML, Patel JB, Glaubiger SA, Falk RJ, Jennette JC, Otey CA. Palladin is upregulated in kidney disease and contributes to epithelial cell migration after injury. Sci Rep. 2015;5:7695. Epub 2015/01/13. doi: 10.1038/srep07695. PubMed PMID: 25573828. (Read Abstract)
  15. Cao Y, Liu K, Tian Z, Hogan SL, Yang J, Poulton CJ, Falk RJ, Li W. PTPN22 R620W polymorphism and ANCA disease risk in white populations: a metaanalysis. J Rheumatol. 2015;42(2):292-9. Epub 2014/12/03. doi: 10.3899/jrheum.131430. PubMed PMID: 25448792; PMCID: PMC4314360. (Read Abstract)
  16. Butler AM, Olshan AF, Kshirsagar AV, Edwards JK, Nielsen ME, Wheeler SB, Brookhart MA. Cancer Incidence Among US Medicare ESRD Patients Receiving Hemodialysis, 1996-2009. Am J Kidney Dis. 2015;65(5):763-72. Epub 2015/02/11. doi: 10.1053/j.ajkd.2014.12.013. PubMed PMID: 25662835. (Read Abstract)
  17. Bunch DO, Mendoza CE, Aybar LT, Kotzen ES, Colby KR, Hu Y, Hogan SL, Poulton CJ, Schmitz JL, Falk RJ, Nachman PH, Pendergraft WF, McGregor JG. Gleaning relapse risk from B cell phenotype: decreased CD5+ B cells portend a shorter time to relapse after B cell depletion in patients with ANCA-associated vasculitis. Ann Rheum Dis. 2015. Epub 2015/05/03. doi: 10.1136/annrheumdis-2014-206756. PubMed PMID: 25934841.
  18. Aybar LT, McGregor JG, Hogan SL, Hu Y, Mendoza CE, Brant EJ, Poulton CJ, Henderson CD, Falk RJ, Bunch DO. Reduced CD5(+) CD24(hi) CD38(hi) and interleukin-10(+) regulatory B cells in active anti-neutrophil cytoplasmic autoantibody-associated vasculitis permit increased circulating autoantibodies. Clin Exp Immunol. 2015;180(2):178-88. Epub 2014/11/08. doi: 10.1111/cei.12483. PubMed PMID: 25376552; PMCID: PMC4408152. (Read Abstract)

2014 Publications

  1. Xiao H, Dairaghi DJ, Powers JP, Ertl LS, Baumgart T, Wang Y, Seitz LC, Penfold ME, Gan L, Hu P, Lu B, Gerard NP, Gerard C, Schall TJ, Jaen JC, Falk RJ, Jennette JC. C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol. 2014;25(2):225-31. Epub 2013/11/02. doi: 10.1681/asn.2013020143. PubMed PMID: 24179165; PMCID: PMC3904560. (Read Abstract)
  2. Selewski DT, Massengill SF, Troost JP, Wickman L, Messer KL, Herreshoff E, Bowers C, Ferris ME, Mahan JD, Greenbaum LA, MacHardy J, Kapur G, Chand DH, Goebel J, Barletta GM, Geary D, Kershaw DB, Pan CG, Gbadegesin R, Hidalgo G, Lane JC, Leiser JD, Song PX, Thissen D, Liu Y, Gross HE, DeWalt DA, Gipson DS. Gaining the Patient Reported Outcomes Measurement Information System (PROMIS) perspective in chronic kidney disease: a Midwest Pediatric Nephrology Consortium study. Pediatr Nephrol. 2014;29(12):2347-56. Epub 2014/06/09. doi: 10.1007/s00467-014-2858-8. PubMed PMID: 24908324; PMCID: PMC4213233. (Read Abstract)
  3. Naik RP, Derebail VK, Grams ME, Franceschini N, Auer PL, Peloso GM, Young BA, Lettre G, Peralta CA, Katz R, Hyacinth HI, Quarells RC, Grove ML, Bick AG, Fontanillas P, Rich SS, Smith JD, Boerwinkle E, Rosamond WD, Ito K, Lanzkron S, Coresh J, Correa A, Sarto GE, Key NS, Jacobs DR, Kathiresan S, Bibbins-Domingo K, Kshirsagar AV, Wilson JG, Reiner AP. Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans. JAMA. 2014;312(20):2115-25. Epub 2014/11/14. doi: 10.1001/jama.2014.15063. PubMed PMID: 25393378; PMCID: PMC4356116. (Read Abstract)
  4. Lee T, Gasim A, Derebail VK, Chung Y, McGregor JG, Lionaki S, Poulton CJ, Hogan SL, Jennette JC, Falk RJ, Nachman PH. Predictors of treatment outcomes in ANCA-associated vasculitis with severe kidney failure. Clin J Am Soc Nephrol. 2014;9(5):905-13. Epub 2014/03/01. doi: 10.2215/cjn.08290813. PubMed PMID: 24578329; PMCID: PMC4011446. (Read Abstract)
  5. Lee T, Biddle AK, Lionaki S, Derebail VK, Barbour SJ, Tannous S, Hladunewich MA, Hu Y, Poulton CJ, Mahoney SL, Charles Jennette J, Hogan SL, Falk RJ, Cattran DC, Reich HN, Nachman PH. Personalized prophylactic anticoagulation decision analysis in patients with membranous nephropathy. Kidney Int. 2014;85(6):1412-20. Epub 2013/12/18. doi: 10.1038/ki.2013.476. PubMed PMID: 24336031; PMCID: PMC4040154. (Read Abstract)
  6. Layton JB, Klemmer PJ, Christiansen CF, Bomback AS, Baron JA, Sandler RS, Kshirsagar AV. Sodium phosphate does not increase risk for acute kidney injury after routine colonoscopy, compared with polyethylene glycol. Clin Gastroenterol Hepatol. 2014;12(9):1514-21 e3. Epub 2014/02/04. doi: 10.1016/j.cgh.2014.01.034. PubMed PMID: 24486407. (Read Abstract)
  7. Joy MS, Roberts BV, Wang J, Hu Y, Hogan SL, Falk RJ. A pilot study of leukocyte expression patterns for drug metabolizing enzyme and transporter transcripts in autoimmune glomerulonephritis. Int J Clin Pharmacol Ther. 2014;52(4):303-13. Epub 2014/02/20. doi: 10.5414/cp201972. PubMed PMID: 24548980; PMCID: PMC4123858. (Read Abstract)
  8. Joy MS, Frye RF, Nolin TD, Roberts BV, La MK, Wang J, Brouwer KL, Dooley MA, Falk RJ. In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases. Pharmacotherapy. 2014;34(2):114-22. Epub 2013/09/17. doi: 10.1002/phar.1347. PubMed PMID: 24038489; PMCID: PMC3945423. (Read Abstract)
  9. Jennette JC, Falk RJ. B cell-mediated pathogenesis of ANCA-mediated vasculitis. Semin Immunopathol. 2014;36(3):327-38. Epub 2014/04/30. doi: 10.1007/s00281-014-0431-y. PubMed PMID: 24777746; PMCID: PMC4084547. (Read Abstract)
  10. Jennette JC, Falk RJ. Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease. Nat Rev Rheumatol. 2014;10(8):463-73. Epub 2014/07/09. doi: 10.1038/nrrheum.2014.103. PubMed PMID: 25003769. (Read Abstract)
  11. Geetha D, Poulton CJ, Hu Y, Seo P, McGregor JA, Falk RJ, Hogan SL. Clinical characteristics and outcome of pauci-immune glomerulonephritis in African Americans. Semin Arthritis Rheum. 2014;43(6):778-83. Epub 2014/01/07. doi: 10.1016/j.semarthrit.2013.11.011. PubMed PMID: 24387818; PMCID: PMC4086456. (Read Abstract)
  12. Freburger JK, Ellis AR, Kshirsagar AV, Wang L, Brookhart MA. Comparative short-term safety of bolus versus maintenance iron dosing in hemodialysis patients: a replication study. BMC Nephrol. 2014;15:154. Epub 2014/09/24. doi: 10.1186/1471-2369-15-154. PubMed PMID: 25245951; PMCID: PMC4182851. (Read Abstract)
  13. Derebail VK, Lacson EK, Jr., Kshirsagar AV, Key NS, Hogan SL, Hakim RM, Mooney A, Jani CM, Johnson C, Hu Y, Falk RJ, Lazarus JM. Sickle trait in African-American hemodialysis patients and higher erythropoiesis-stimulating agent dose. J Am Soc Nephrol. 2014;25(4):819-26. Epub 2014/01/25. doi: 10.1681/asn.2013060575. PubMed PMID: 24459231; PMCID: PMC3968502. (Read Abstract)
  14. Caughey MC, Loehr LR, Key NS, Derebail VK, Gottesman RF, Kshirsagar AV, Grove ML, Heiss G. Sickle cell trait and incident ischemic stroke in the Atherosclerosis Risk in Communities study. Stroke. 2014;45(10):2863-7. Epub 2014/08/21. doi: 10.1161/strokeaha.114.006110. PubMed PMID: 25139879; PMCID: PMC4174726. (Read Abstract)
  15. Butler AM, Kshirsagar AV, Brookhart MA. Opioid use in the US hemodialysis population. Am J Kidney Dis. 2014;63(1):171-3. Epub 2013/10/23. doi: 10.1053/j.ajkd.2013.09.008. PubMed PMID: 24145020; PMCID: PMC4086908. (Letter to the Editor)
  16. Brookhart MA, Todd JV, Li X, Reams BD, Pate V, Kshirsagar AV. Estimation of biomarker distributions using laboratory data collected during routine delivery of medical care. Ann Epidemiol. 2014;24(10):754-61. Epub 2014/09/23. doi: 10.1016/j.annepidem.2014.07.013. PubMed PMID: 25238941; PMCID: PMC4476533. (Read Abstract)
  17. Brice JH, Foster MB, Principe S, Moss C, Shofer FS, Falk RJ, Ferris ME, DeWalt DA. Single-item or two-item literacy screener to predict the S-TOFHLA among adult hemodialysis patients. Patient Educ Couns. 2014;94(1):71-5. Epub 2013/10/31. doi: 10.1016/j.pec.2013.09.020. PubMed PMID: 24169024. (Read Abstract)
  18. Berg EA, McGregor JG, Burkart ME, Poulton CJ, Hu Y, Falk RJ, Hogan SL. What Everybody is Doing but No One is Talking About: Use of Complementary and Alternative Medicine in the ANCA Associated Vasculitis Population. J Autoimmune Dis Rheumatol. 2014;2(3):74-91. Epub 2015/01/20. PubMed PMID: 25599078; PMCID: PMC4295716. (Read Abstract)
  19. Bates CM, Charlton JR, Ferris ME, Hildebrandt F, Hoshizaki DK, Warady BA, Moxey-Mims MM. Pediatric kidney disease: tracking onset and improving clinical outcomes. Clin J Am Soc Nephrol. 2014;9(6):1141-3. Epub 2014/03/22. doi: 10.2215/cjn.00860114. PubMed PMID: 24651076; PMCID: PMC4046717. (Read Abstract)